Carboxylic acid derivatives with an aggregation-inhibiting...

Details Carboxylic acid derivatives with an aggregation-inhibiting... Carboxylic acid derivatives with an aggregation-inhibiting...

C - Chemistry, Metallurgy

07

D

C07D 211/34 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) C07D 211/46 (2006.01) C07D 211/58 (2006.01) C07D 295/155 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2244860

The invention concerns carboxylic acid derivatives of the general formula (I), in which Ra to Rc, A, B, D, E and X1 to X3 are as defined in claim 1, their stereoisomers, including mixtures and salts, in particular physiologically tolerated salts, with inorganic or organic acids or bases, which exhibit useful pharmacological properties, preferably an aggregation-inhibiting action. The invention also concerns drugs containing such compounds, their use and methods of preparing them.

L'invention a pour objet des dérivés d'acides carboxyliques de formule générale (I), dans laquelle R¿a? à R¿c?, A, B, D, E et X¿1? à X¿3? sont tels que définis dans la revendication 1, leurs tautomères, leur stéréoisomères, y compris leurs mélanges et leurs sels, en particulier leurs sels physiologiquement tolérés avec des acides organiques ou des bases, lesquels présentent des propriétés pharmacologiques remarquables, avantageusement des effets inhibant l'agrégation. L'invention a également pour objet des médicaments renfermant ces composés, leur utilisation et leurs procédés de fabrication.

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