Carboxylic acid hydrazides and processes for their manufacture

A - Human Necessities – 61 – K

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A61K 31/24 (2006.01) A61K 31/15 (2006.01) A61K 31/16 (2006.01) A61K 31/19 (2006.01) A61K 31/195 (2006.01) A61K 31/22 (2006.01)

Patent

CA 1146961

Abstract of the Disclosure New carboxylic acid hydrazides of the formula Image (I), in which R represents an optionally esterified carboxy group, and salts of the compound of the formula I, in which R represents carboxy, possess antithrombotic properties and can be used as medicinal active substances in pharmaceutical preparations. They are manufactured, for example, by hydrolysing 1,2-diphenyl-4-(phenylthio- ethyl)pyrazolidin-3,5-dione or condensing a 2-(2-phenylthio- ethyl)malonic acid monoester with hydrazobenzene.

351672

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