Carboxylic acid-metal ion-acid complexes

Details Carboxylic acid-metal ion-acid complexes Carboxylic acid-metal ion-acid complexes

A - Human Necessities

61

K

A61K 31/495 (2006.01) A61K 31/555 (2006.01) A61K 33/06 (2006.01) C07F 3/00 (2006.01) C07F 5/06 (2006.01)

Patent

CA 2072366

Compositions of a quinolone carboxylic acids useful for oral or parenteral administration to a human or veterinary patient are disclosed which comprise quinolone carboxylic acid--metal ion--acid complexes in combination with a physiologically accept- able carrier and haying a pH of about 4 to about 10, as well as a method for their production and use in treatment. Such composi- tions are found to cause unexpectedly low levels of vein irritation upon intravenous administration.

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