Carboxylic acids and isosteres of n-heterocyclic compounds...

Details Carboxylic acids and isosteres of n-heterocyclic compounds... Carboxylic acids and isosteres of n-heterocyclic compounds...

A - Human Necessities

61

K

A61K 31/435 (2006.01) A61K 31/00 (2006.01) A61K 31/40 (2006.01) A61K 31/401 (2006.01) A61K 31/4353 (2006.01) A61K 31/44 (2006.01) A61K 31/444 (2006.01) A61K 31/445 (2006.01) A61K 31/453 (2006.01) A61K 31/4535 (2006.01) A61K 31/4545 (2006.01) A61K 31/50 (2006.01) A61K 31/5025 (2006.01) A61K 38/18 (2006.01) C07K 14/48 (2006.01)

Patent

CA 2340419

This invention relates to novel compositions and uses of N-heterocyclic carboxylic acids and carboxylic acid isosteres which have affinity for an FKBP- type (FKBP12) immunophilin and which inhibit its rotamase activity. These compounds can be immunosuppressive or non immunosuppressive for treating a vision disorder, improving vision, treating memory impairment or enhancing memory performance in an animal.

L'invention concerne des nouvelles compositions et utilisations d'acides carboxyliques N-hétérocycliques et d'isostères de l'acide carboxylique, servant à traiter un trouble de la vision, à améliorer la vision, à traiter des défauts de mémoire ou à améliorer les performances de celle-ci, chez un animal.

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