C - Chemistry – Metallurgy – 08 – B
Patent
C - Chemistry, Metallurgy
08
B
C08B 37/00 (2006.01) A61K 47/48 (2006.01)
Patent
CA 2081025
ABSTRACT A carboxymethylmannoglucan comprising tetrasaccharide units represented by the following general formula (I) and salt thereof. Further, the invention discloses; a carboxymethylmannoglucan derivative and salt thereof produced by subjecting part of the whole of mannose of the tetrasaccharide units to ring opening and subjecting part or the whole of glucose which constitute the main chain but have no mannose as a branch Image (I) wherein R1 to R12 each represent a hydrogen atom of a carboxymethyl group. The compounds are useful as carrier for delaying the disappearance of a drug in the blood and for enhancing the organotropism of the drug for a carcinoma.
Aono Katsutoshi
Inoue Kazuhiro
Ito Teruomi
Kawaguchi Takayuki
Okuno Satoshi
Drug Delivery System Institute Ltd.
Fetherstonhaugh & Co.
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