Card-4 molecules and uses thereof

Details Card-4 molecules and uses thereof Card-4 molecules and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A01K 67/027 (2006.01) A61K 35/00 (2006.01)

Patent

CA 2486603

The invention provides methods of using CARD-4 molecules to screen for modulators of LPS-induced cell signaling pathways. Also included are CARD-4 deficient mice, methods of modulating LPS-induced cell signaling pathways, and methods of treating or preventing bacterial infections.

Cette invention se rapporte à des procédés d'utilisation des molécules CARD-4 pour crible les modulateurs des voies de signalisation cellulaire induites par LIPOPOLYSACCHARIDE (LPS). Cette invention concerne également des souris ayant une déficience en molécules CARD-4, des procédés de modulation des voies de signalisation cellulaire induites par LPS, et des procédés de traitement ou de prévention des infections bactériennes.

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