Card domain containing polypeptides, encoding nucleic acids,...

Details Card domain containing polypeptides, encoding nucleic acids,... Card domain containing polypeptides, encoding nucleic acids,...

C - Chemistry, Metallurgy

12

N

C12N 15/57 (2006.01) C07H 21/00 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C07K 16/00 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2410096

The invention provides caspase recruitment domain (CARD) -containing polypeptides, CARD, NB-ARC, ANGIO-R, LRR and SAM domains therefrom, as well as encoding nucleic acid molecules and specific antibodies. The invention also provides related screening, diagnostic and therapeutic methods.

L'invention concerne des polypeptides contenant un domaine de recrutement des caspases (CARD), des domaines CARD, NB-ARC, ANGIO-R, LRR et SAM, ainsi que des molécules d'acide nucléique et des anti-corps spécifiques. L'invention concerne également des méthodes de criblage, des méthodes de diagnostic et des méthodes thérapeutiques associées.

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