Cardiac pacing modality having improved blanking, timing,...

A - Human Necessities – 61 – N

Patent

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A61N 1/362 (2006.01)

Patent

CA 2541386

The present invention relates to the secure delivery of an extra-systolic stimulation (ESS) therapy to treat cardiac dysfunction that employs atrial and/or ventricular extra-systoles via pacing-like stimulation of the heart. These extra-systoles must be timed correctly to achieve beneficial effects on myocardial mechanics (benefit) while maintaining an extremely low level of risk of arrhythmia induction and excellent ICD-like arrhythmia sensing and detection (security). Further experience with ESS has led to improved implementation methods that depend on better blanking, ESS stimulation timing (of an "extra-systolic interval" or ESI), and ESS therapy delivery options and guidance. These methods may be employed individually or in combinations in an external or implantable ESS therapy delivery device.

La présente invention concerne l'administration sécurisée d'une thérapie de stimulation extra-systolique en vue de traiter un dysfonctionnement cardiaque au moyen d'extra-systoles atriales et/ou ventriculaires par stimulation du coeur similaire à l'entraînement. Ces extra-systoles doivent être synchronisées correctement afin de parvenir aux effets bénéfiques engendrés sur les mécanismes myocardiaques, tandis que sont maintenus un niveau extrêmement bas de risque d'induction d'arythmie et une excellente détection d'arythmie similaire à la CIM (sécurité). Une autre expérience liée à la stimulation extra-systolique a débouché sur de meilleures méthodes d'implémentation qui dépendent d'une meilleure suppression, d'une temporisation de la stimulation extra-systolique ("d'un intervalle extra-systolique") et de guidage et d'options d'administration thérapeutique de stimulation extra-systolique. Ces méthodes peuvent être utilisées individuellement ou en combinaison avec un dispositif d'administration thérapeutique de stimulation extra-systolique externe ou implantable.

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