Cardiac transplantation of stem cells for the treatment of...

A - Human Necessities – 61 – K

Patent

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A61K 35/00 (2006.01) C12N 5/071 (2010.01) C12N 5/074 (2010.01) A61K 35/12 (2006.01) A61K 38/18 (2006.01) C12N 5/077 (2010.01)

Patent

CA 2465672

A method of treating heart failure and improving cardiac function by administering stem cells to a heart in need of treatment, whereby the stem cells differentiate into cardiac muscle cells thereby treating heart failure and improving cardiac function. A method of enriching or regenerating damaged myocardium by administering stem cells to damaged myocardium. Stem cell products and/or stem cells for use in treating heart failure. A composition for enriching and regenerating damaged myocardium, the composition having stem cell products in a pharmaceutically acceptable carrier.

L'invention concerne une méthode de traitement de l'insuffisance cardiaque et d'amélioration de la fonction cardiaque par administration de cellules souches dans le coeur d'un patient nécessitant un traitement, les cellules souches se différenciant en cellules musculaires cardiaques et permettant ainsi de traiter l'insuffisance cardiaque et d'améliorer la fonction cardiaque. L'invention concerne également une méthode visant à enrichir ou à régénérer un myocarde endommagé par l'administration de cellules souches dans un myocarde endommagé. L'invention concerne en outre des produits de cellules souches et/ou des cellules souches utilisés dans le traitement de l'insuffisance cardiaque. L'invention concerne enfin une composition destinée à enrichir et à régénérer un myocarde endommagé, la composition comprenant des produits de cellules souches dans un excipient acceptable d'un point de vue pharmaceutique.

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