Cardiac vulnerability tracking by t-wave alternans analysis

Details Cardiac vulnerability tracking by t-wave alternans analysis Cardiac vulnerability tracking by t-wave alternans analysis

A - Human Necessities

61

B

A61B 5/0452 (2006.01) A61B 5/046 (2006.01)

Patent

CA 2104450

2104450 9214401 PCTABS00015 A method for dynamic tracking of cardiac vulnerability to ventricular fibrillation is disclosed. A heart is monitored to sense an ECG signal (202) which is amplified (206) and low-pass filtered (208) before it is digitally sampled (210) and stored (212). The location of the T-wave in each R-R interval of the ECG is estimated and each T-wave is partitioned into a plurality of time divisions. The sampled ECG signal in each of the time divisions is summed together and a time series is formed for each of the time divisions such that each time series includes corresponding sums from corresponding time divisions from successive T-waves. Each time series is detrended in order to eliminate the effects of drift and DC bias, and then a method of dynamic estimation is performed on each time series to estimate the amplitude of alternation for each time division (214).

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