Cardioprotective composition and uses thereof

Details Cardioprotective composition and uses thereof Cardioprotective composition and uses thereof

A - Human Necessities

61

K

A61K 31/19 (2006.01) A61K 31/23 (2006.01) A61K 31/355 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2373050

A cardioprotective composition for protecting heart against oxidative stress and methods for using and preparing the same. More particularly, the cardioprotective composition of the invention comprises a mixture of pyruvate, antioxidant, and lipid(s) such as fatty acids. The cardioprotective composition could be used for the treatment of heart attack/failure, the treatment of ischemic cardiopathy, the conservation of heart before and during transplantation, and the treatment of heart oxidative stress related conditions.

L'invention concerne une composition cardioprotectrice visant à protéger le coeur contre le stress oxydant et des procédés de préparation et d'utilisation de cette composition. En particulier, la composition cardioprotectrice comprend un mélange de pyruvate, d'un antioxydant et de lipide(s) tel(s) que des acides gras. La composition cardioprotectrice peut s'utiliser dans le traitement de la crise et de l'insuffisance cardiaques, de la cardiopathie ischémique, pour la conservation du coeur avant et pendant la transplantation et dans le traitement des états liés au stress oxydant du coeur.

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