Cardioprotective composition comprising ceruloplasmin and...

A - Human Necessities – 61 – K

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Details

A61K 38/57 (2006.01) A61K 31/19 (2006.01) A61K 31/20 (2006.01) A61K 38/44 (2006.01) A61K 45/06 (2006.01) A61P 39/06 (2006.01)

Patent

CA 2373054

A cardioprotective composition for protecting heart against oxidative stress and methods for using and preparing the same. More particularly, the cardioprotective composition of the invention comprises a mixture of pyruvate, antioxidant, fatty acids and ceruloplasmin. The cardioprotective composition could be used for the treatment of heart attack/failure, the treatment of ischemic cardiopathy, the conservation of heart before and during transplantation, and the treatment heart oxidative stress related conditions.

Composition cardioprotectrice utilisée pour protéger le coeur contre le stress oxydant et procédés d'utilisation et de préparation de cette composition. De manière plus spécifique, la composition cardioprotectrice selon la présente invention contient un mélange de pyruvate, d'antioxydant, d'acides gras et de céruloplasmine. Cette composition cardioprotectrice pourrait être utilisée pour traiter les crises cardiaques et/ou l'insuffisance cardiaque, pour traiter la cardiopathie ischémique, pour conserver le coeur avant et pendant une transplantation et pour traiter les états associés au stress oxydant du coeur.

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