Cardiotonic composition

A - Human Necessities – 61 – K

Patent

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167/199

A61K 9/48 (2006.01)

Patent

CA 1046410

ABSTRACT OF THE DISCLOSURE A cardiotonic dosage unit form comprises a soft gelatine capsule containing a liquid cardiotonic composition comprising (a) a cardiac glycoside, preferably digitoxin or digoxin; (b) dimethyl formamide or dimethyl acetamide; and (c) a liquid polyethylene glycol and also, optionally, (d) propylene glycol or glycerin. The weight ratio of dimethyl acetamide or dimethyl formamide to cardiac glyceride is from 5:1 to 15:1 and the polyethylene glycol forms at least 75% by weight of the total composition contained in the gelatine capsule.

223484

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