C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
260/19, 260/8
C07J 43/00 (2006.01)
Patent
CA 1049499
Abstract of the Disclosure The invention relates to novel steroid compounds having the formula Image and their glycoside dorivatives containing a pyridazine ring, in which particularly the substituent R4 is a hy- droxy group or a hoxopyranoside unit or a chain of two or three hexopyranoside units, as it is normally found in the molecule of the natural glycosides; one or even all the hydroxy groups contained in the R4 can be either free or etherified or esterified with either a simple carboxylic acid or a carboxylic acid bearing basic groups, or three acetalized with an aldehyde or a ketone, depending on the position and the orientation of a pair of hydroxy groups. The subject compounds are endowed with cardioto- nic activity, The invention moreover relates to the pro- cess for the preparation of the above compounds and to their therapeutic use.
233045
Casagrande Cesare
Ferrari Giorgio
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