C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) C07K 14/47 (2006.01) C12N 9/12 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2353773
The invention provides isolated nucleic acids molecules, designated CARK nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing CARK nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a CARK gene has been introduced or disrupted. The invention still further provides isolated CARK proteins, fusion proteins, antigenic peptides and anti-CARK antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
L'invention concerne des molécules d'acide nucléique isolées, désignées sous le nom de molécules d'acide nucléique CARK. L'invention concerne également des molécules d'acide nucléique anti sens, des vecteurs d'expression recombinants contenant des molécules d'acide nucléique CARK, des cellules hôtes dans lesquelles ont été introduits les vecteurs d'expression et des animaux transgéniques chez lesquels un gène CARK a été introduit ou a subi une disruption. L'invention concerne aussi des protéines isolées CARK, des protéines de fusion, des peptides antigéniques et des anticorps anti-CARK. L'invention propose également des méthodes de diagnostic utilisant les compositions de l'invention.
Borden Ladner Gervais Llp
Millennium Pharmaceuticals Inc.
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