Carrier-free orodispersible and/or dispersible solid...

A - Human Necessities – 61 – K

Patent

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A61K 9/20 (2006.01)

Patent

CA 2697893

The invention relates to an orodispersible and/or dispersible solid composition that comprises: (a) from 0.1 to 59 wt % of at least one active substance having a grading not exceeding 50 µm; (b) from 40 to 99 wt % of at least one water-soluble dilution agent without any noticeable effect; from 0.1 to 15 wt % of at least one disintegrating agent; and (d) from 0.05 t 10 wt % of at least one sweetening agent having a grading lower than 50 µm, the weight percentages being expressed relative to the total weight of the composition. The invention also relates to the use of the composition as a drug, a food additive or in cosmetics, and to a method for preparing an orodispersible and/or dispersible compound using said composition.

La présente invention concerne une composition solide, orodispersible et/ou dispersible comprenant (a) de 0,1 à 59 % en poids d'au moins une substance active de granulométrie n'excédant pas 50 µm; (b) de 40 à 99 % en poids d'au moins un agent diluant, sans effet notoire, non-soluble dans l'eau; (c) de 0,1 à 15 % en poids d'au moins un agent désintégrant; et (d) de 0,05 à % en poids d'au moins un agent édulcorant de granulométrie inférieure à 50 µm, les pourcentages en poids étant exprimés par rapport au poids total de ladite composition. La présente invention concerne également l'utilisation de ladite composition en tant que médicament, que complément alimentaire ou en cosmétique et un procédé de préparation d'un composé orodispersible et/ou dispersible mettant en oeuvre ladite composition.

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