A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/72 (2006.01) A61K 9/12 (2006.01) A61K 9/14 (2006.01)
Patent
CA 2211874
A powder for use in a dry powder inhaler includes active particles and carrier particles for carrying the active particles. The powder further includes additive material (4) on the surfaces of the carrier particles to promote the release of the active particles from the carrier particles on actuation of the inhaler. The powder is such that the active particles are not liable to be released from the carrier particles before actuation of the inhaler. The inclusion of additive material (4) in the powder has been found to give an increased respirable fraction of the active material.
Une poudre à utiliser dans un inhalateur à poudre sèche comprend des particules actives et des particules porteuses servant au transport de ces dernières. Cette poudre porte, de surcroît, sur les faces des particules porteuses, un additif (4) destiné à permettre aux particules actives de se dégager facilement des porteuses lors de la mise en fonctionnement de l'inhalateur. Cette poudre est agencée de telle façon que les particules actives ne sont pas susceptibles de se dégager des porteuses avant la mise en fonctionnement de l'inhalateur. Il s'est avéré que l'adjonction d'additif (4) dans la poudre majorait la partie inhalable de la substance active.
Co-Ordinated Drug Development Limited
Gowling Lafleur Henderson Llp
Vectura Limited
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