Carrier vectors through an epithelium with tight junctions

Details Carrier vectors through an epithelium with tight junctions Carrier vectors through an epithelium with tight junctions

A - Human Necessities

61

K

A61K 38/16 (2006.01) A61K 38/00 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2427896

The invention concerns peptide vectors, comprising a transduction domain, and a nuclear export sequence, for carrying a molecule of interest through an epithelium with tight junctions, such as the blood-brain barrier.

L'invention concerne l'utilisation de vecteurs peptidiques, comprenent un domaine de transduction, et une séquence d'export nucléaire, pour transporter une molécule d'intérêt à travers un épithélium à jonctions serrées, tel que la barrière hémato-méningée.

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