Carriers for combinatorial compound libraries

Details Carriers for combinatorial compound libraries Carriers for combinatorial compound libraries

C - Chemistry, Metallurgy

07

B

C07B 61/00 (2006.01) C07H 1/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 17/02 (2006.01) C07K 17/08 (2006.01) C09B 11/08 (2006.01) C09B 69/10 (2006.01) G01N 15/14 (2006.01)

Patent

CA 2352082

A carrier pre-encoded with information sufficient to distinguish it from a heterogeneous population of carriers is disclosed on which a compound can be synthesised. The carrier has two attributes integrally associated therewith, which attributes are detectable and/or quantifiable during synthesis of the compound and which define a code identifying the carrier before, during and after said synthesis, with the proviso that one of said attributes is other than shape, or surface deformation(s) of the carrier. The invention also encompasses a plurality of carriers that are pre-encoded as above and a method of synthesising and deconvoluting a combinatorial library using such carriers.

L'invention concerne un support pré-codé avec des informations suffisantes à le distinguer dans une population hétérogène de supports, sur lequel il est possible de synthétiser un composé. Ce support possède deux propriétés qui lui sont intégralement associées pouvant être détectées et/ou quantifiées au cours de la synthèse du composé et définissant un code qui identifie ledit support avant, pendant et après la synthèse, à condition qu'une des deux propriétés ne soit pas la taille ou la déformation surfacique du support. L'invention concerne également une pluralité de ces supports pré-codés et une technique utilisant ces supports pour la synthèse et la déconvolution de banques combinatoires.

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