Cartilage-derived stem cells and applications thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/077 (2010.01) C12N 5/074 (2010.01) A61K 35/12 (2006.01) A61K 35/32 (2006.01) C12Q 1/02 (2006.01) C40B 30/06 (2006.01)

Patent

CA 2528679

The invention relates to methods of isolating adult stem cells, to the cells thus isolated and to applications thereof. More specifically, the invention relates to isolated adult stem cells which are derived from dedifferentiated chondrocytes, which can be differentiated and which can give rise to a series of cell lineages, as well as to specific markers present in said cells, such as cell surface antigens. The aforementioned cells can be used, for example, in cell therapy and in the search for and development of novel medicaments.

L'invention concerne des méthodes permettant d'isoler des cellules mères adultes, des cellules isolées au moyen de ces méthodes et leurs applications. Plus particulièrement, l'invention concerne des cellules mères adultes isolées, dérivées de chondrocytes dédifférenciés, pouvant se différencier et donner lieu à une série de lignées cellulaires, comme les marqueurs spécifiques présents dans ces cellules, qui peuvent être des antigènes de surface cellulaire. Ces cellules sont par exemple utilisées en thérapie cellulaire ainsi que dans la recherche et le développement de nouveaux médicaments.

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