A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/48 (2006.01) A61L 27/24 (2006.01) A61L 27/42 (2006.01)
Patent
CA 2600893
The present invention relates to a multilayer struc~ture (1) including a first upper layer (2) consisting of an organic matrix including collagen and at least a lower layer (3, 4, ... 10) consisting of a composite ma~trix including hydroxylapatite and collagen. Further~more, the present invention relates to a cartilaginous substitute including said multilayer structure (1) as well as an osteochondral substitute including said multilayer structure (1) . Finally, the present inven~tion relates to the use of said multilayer structure (1) for the preparation of said cartilaginous substi~tute and said osteochondral substitute for the treat~ment of cartilaginous defects and osteochondral de~fects or for the neo-formation of a cartilaginous tis~sue and/or a subchondral bone tissue.
La présente invention concerne une structure multicouche (1) comprenant une première couche supérieure (2) constituée d'une matrice organique comprenant du collagène et au moins une couche inférieure (3, 4, ... 10) constituée d'une matrice composite comprenant de l'hydroxyapatite et du collagène. En outre la présente invention concerne un substitut cartilagineux intégrant ladite structure multicouche (1) de même qu'un substitut ostéochondrial intégrant ladite structure multicouche(1) . Enfin la présente invention décrit l'utilisation de ladite structure multicouche(1) pour la préparation dudit substitut cartilagineux et dudit substitut ostéochondrial pour le traitement de défauts cartilagineux ou ostéochondriaux ou pour la néo-formation d'un tissu cartilagineux et/ou d'un tissu osseux subchondrial.
de Luca Claudio
Di Fede Sergio
Landi Elena
Pressato Daniele
Tampieri Anna
Fin-Ceramica Faenza S.p.a.
Oyen Wiggs Green & Mutala Llp
LandOfFree
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