Cartilaginous neo-tissue capable of being grafted

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/38 (2006.01) A61L 27/20 (2006.01) A61L 27/52 (2006.01) C12N 5/00 (2006.01) C12N 5/06 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2442734

The invention concerns a cartilaginous neo-tissue capable of being grafted characterised in that it consists of rows of more or less parallel cells, having a cellular maturation gradient oriented from a specific zone towards its periphery. During the preparation of the cartilaginous neo-tissue with a chitosan hydrogel, the specific zone corresponds to a zone of junction between the cells and the chitosan hydrogel in contact with which the tissue develops.

Le néo-tissu cartilagineux greffable caractérisé est constitué de rangées de cellules plus ou moins parallèles, présentant un gradient de maturation cellulaire orienté depuis une zone déterminée vers sa périphérie. Lors de la préparation du néo-tissu cartilagineux avec un hydrogel de chitosane, la zone déterminée correspond à la zone de jonction des cellules avec l'hydrogel de chitosane au contact duquel le néo-tissu se développe.

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