Casb414: antigen overexpressed in several tumors

Details Casb414: antigen overexpressed in several tumors Casb414: antigen overexpressed in several tumors

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 39/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2323601

CASB414 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CASB414 polypeptides and polynucleotides in diagnostics, and vaccines for prophylactic and therapeutic treatment of cancers, particularly colon cancers, autoimmune diseases, and related conditions.

L'invention concerne des polypeptides et des polynucléotides CASB414 et des procédés de production desdits polypeptides CASB414 par des techniques de recombinaison. Elle porte aussi sur des procédés d'utilisation des polynucléotides et des polypeptides CASB414 dans les diagnostics, et sur des vaccins pour le traitement prophylactique et thérapeutique de cancers, notamment des cancers du colon, de maladies auto-immunes et d'états associés.

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