Casein derived peptides and uses thereof in therapy

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) C12N 5/0797 (2010.01) A61K 35/14 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2401550

Biologically active peptides that are derived from or are similar to sequences identical with the N-terminus of the .alpha.S1 fraction of milk casein. These peptides are capable of stimulating and enhancing immune response, protecting against viral infection, normalizing serum cholesterol levels, and stimulating hematopoiesis. The casein-derived peptides are non-toxic and can be used to treat and prevent immune pathologies, hypercholesterolemia, hematological disorders and viral-related diseases.

L'invention porte sur des peptides biologiquement actifs dérivant de ou similaires à des séquences identiques à la fraction alpha S1 du terminus N de la caséine du lait. Lesdits peptides, qui sont capables de stimuler et d'accroître la réponse immunitaire, de protéger contre les infections virales, de normaliser les niveaux du cholestérol sérique, et de stimuler l'hématopoïèse, sont non toxiques, et peuvent servir au traitement et à la prévention de pathologies immunitaires, de l'hypercholestérolémie, de troubles hématologiques, et de maladies virales.

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