Casein hydrolyzate, process for producing the same and use...

Details Casein hydrolyzate, process for producing the same and use... Casein hydrolyzate, process for producing the same and use...

C - Chemistry, Metallurgy

12

P

C12P 21/06 (2006.01) A61K 38/01 (2006.01) A61P 9/12 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2546497

A casein hydrolyzate, especially one whose in vivo manifestation of functions, such as antihypertensive activity, is promising, which casein hydrolyzate comprises a peptide, such as a nonbiodegradable peptide having minimized its in vivo zymolytic activity, and free amino acids; a process for producing the same; and use thereof. In particular, the casein hydrolyzate is obtained by hydrolyzing animal milk casein into an average chain length of 2.1 or less in terms of amino acid residue quantity, and contains free amino acids and a peptide, such as a nonbiodegradable peptide, e.g., XaaPro or XaaProPro. The casein hydrolyzate exhibits an ACE inhibitory activity or antihypertensive activity.

L'invention concerne un hydrolysat de caséine, en particulier, un hydrolysat de caséine dont la manifestation de fonctions in vivo, telles que l'activité hypertensive, est prometteuse. Ledit hydrolysat de caséine comprend un peptide, tel qu'un peptide non biodégradable dont l'activité zymolitique in vivo est réduite, et des acides aminés libres. L'invention concerne également un procédé de production d'hydrolyzat de caséine et son utilisation. Cet hydrolysat de caséine est notamment obtenu par hydrolysation de la caséine du lait d'animal en une longueur de chaîne moyenne de 2,1 ou moins en termes de quantité résiduelle d'acide aminé, et contient des acides aminés libres et un peptide, tel qu'un peptide non biodégradable, par exemple, XaaPro ou XaaProPro. L'hydrolysat de caséine présente une activité inhibitrice de ACE ou une activité antihypertensive.

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