Casein kinase 2 antisense therapy

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/113 (2010.01) A61K 31/7088 (2006.01) C07H 21/04 (2006.01) C12N 9/12 (2006.01) C12N 15/54 (2006.01)

Patent

CA 2590619

The invention provides for antisense oligonucleotides that hybridize to casein kinase 2 nucleic acid sequences and methods of using such antisense oligonucleotides to inhibit expression of casein kinase 2 and reduce the size of solid tumors.

L'invention concerne des oligonucléotides antisens s'hybridant à des séquences d'acides nucléiques de caséine kinase 2 ainsi que des méthodes d'utilisation de ces oligonucléotides antisens pour inhiber l'expression de la caséine kinase 2 et réduire la taille de tumeurs solides.

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