C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/37 (2006.01) G01N 33/542 (2006.01)
Patent
CA 2695244
The present invention relates to molecular probes of the formula (I) {L1-R1-L} n A CO-NH R2-L2 (I) as defined herein that allow for the observation of the catalytic activity ofa selected capasein in vitroassays, in cells or in multicellular organisms, a method for their preparation and the use thereof.
La présente invention concerne des sondes moléculaires de la formule (I) {L1-R1-L} n A CO-NH R2-L2 (I) telle que définie dans le présent document qui permettent l'observation de l'activité catalytique d'une capase sélectionnée dans des essais in vitro, dans des cellules ou dans des organismes multicellulaires, un procédé permettant leur préparation et l'utilisation de celles-ci.
Kindermann Maik
Miniejew Catherine
Wendt Karl-Ulrich
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis
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