Caspase-inhibitory-factor (cif) and uses thereof

Details Caspase-inhibitory-factor (cif) and uses thereof Caspase-inhibitory-factor (cif) and uses thereof

C - Chemistry, Metallurgy

12

Q

C12Q 1/37 (2006.01) A61K 31/00 (2006.01) A61K 38/00 (2006.01) A61K 38/57 (2006.01) A61P 25/00 (2006.01) C07K 14/81 (2006.01)

Patent

CA 2401606

The present invention relates to the identification of a caspase inhibitory factor (CIF) and to the establishment of a screening procedure to find caspase inhibitors in human neurons. More particularly, the invention relates to a 17- .beta.-estradiol inducible caspase-6 inhibitory factor.

L'invention concerne l'identification d'un facteur inhibiteur de caspase et l'établissement d'une procédure de criblage visant à déterminer des inhibiteurs de caspase dans les neurones humains. Plus particulièrement, l'invention concerne un facteur inhibiteur de caspase-6 pouvant être induit à travers le 17-.beta.-estradiol.

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