Castanospermine esters and glycosides

Details Castanospermine esters and glycosides Castanospermine esters and glycosides

C - Chemistry, Metallurgy

07

D

167/202, 260/228

C07D 471/04 (2006.01) A61K 31/445 (2006.01) C07H 17/02 (2006.01)

Patent

CA 1315276

ABSTRACT OF THE DISCLOSURE Castanospermine mono- and di-esters and glycosides active as inhibitors of carbohydrate digestive enzymes and useful in treating diabetes are described herein. The compounds are prepared by the reaction of castanospermine with an appropriate acid halide or anhydride or with an appropriate glycosyl halide or glycosyl acetimidate under conditions which would favor the isolation of the mono- and di-esterified and glycosylated products. MO1293 US

570177

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