Catalysts for asymmetric syntheses containing rigid chiral...

C - Chemistry – Metallurgy – 07 – F

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C07F 9/46 (2006.01) C07B 53/00 (2006.01) C07C 45/50 (2006.01) C07F 9/50 (2006.01) C07F 9/6568 (2006.01) C07F 9/6574 (2006.01) C07F 15/00 (2006.01)

Patent

CA 2309193

This invention is to develop novel transition metal catalysts for the pratical synthesis of important chiral molecules. The invention emphasizes asymmetric catalysis based on chiral bidentate phosphine ligands with cyclic ring structures which could be used to restrict conformational flexibility of the ligands and thus the efficiency of chiral transfer can be enhanced through the ligand rigidity.

Cette invention a pour but de mettre au point de nouveaux catalyseurs à métaux de transition, servant à la synthèse pratique de molécules chirales importantes. Cette invention met l'accent sur la catalyse asymétrique basée sur des ligands de phosphine bidentés chiraux avec des structures de chaînes cycliques, pouvant servir à limiter la flexibilité de conformation des ligands, l'efficacité du transfert chiral pouvant par conséquent être améliorée grâce à la rigidité des ligands.

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