Catalytic antibodies against cocaine and methods of using...

Details Catalytic antibodies against cocaine and methods of using... Catalytic antibodies against cocaine and methods of using...

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 47/48 (2006.01) C07D 451/02 (2006.01) C07F 9/547 (2006.01) C07F 9/6561 (2006.01) C07F 9/6571 (2006.01) C07F 9/6584 (2006.01) C07H 21/00 (2006.01) C07K 16/44 (2006.01) C12N 9/00 (2006.01) C12N 9/18 (2006.01) C12P 21/08 (2006.01) C12Q 1/44 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2132982

This invention provides compounds which are analogs to the hydrolysis transition-state of a cocaine benzoyl ester group. This invention also provides such analogs linked to carrier proteins, and antibodies thereto. This invention further provides pharmaceutical composition for decreasing cocaine concentration in a subject using the antibodies produced.

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