C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61K 31/70 (2006.01) C12N 15/10 (2006.01) C12N 15/11 (2006.01)
Patent
CA 2264246
The present invention concerns nucleic acid molecules, or complex of molecules, which have no catalytic activity in the absence of a specific co- factor, and feature catalytic activity only in the presence of a specific co- factor. The present invention further concerns methods for the production of said molecules, or complex of molecules, particularly utilizing in vitro evolution, as well as their usage in diagnostics and therapeutics.
La présente invention concerne des molécules d'acides nucléiques ou un complexe de ces molécules, lesquelles ne possèdent pas d'activité catalytique en l'absence d'un cofacteur spécifique et ne démontrent cette activité catalytique qu'uniquement en présence de ce cofacteur. L'invention concerne en outre des procédés de production de telles molécules, ou d'un complexe de celles-ci, procédés mettant en oeuvre notamment une évolution in vitro, et elle concerne également l'utilisation de ces molécules ou d'un complexe de celles-ci dans des méthodes diagnostiques et thérapeutiques.
Asher Nathan
Ellington Andy
Tikochinski Yaron
Gowling Lafleur Henderson Llp
Intelligene Ltd.
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