Catalyzed carbonylation in the synthesis of angiotensin ii...

Details Catalyzed carbonylation in the synthesis of angiotensin ii... Catalyzed carbonylation in the synthesis of angiotensin ii...

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01)

Patent

CA 2719068

One embodiment disclosed in the invention is the efficient synthesis of halogenated biaryl starting material via Grignard chemistry and the use thereof. Another embodiment of the invention is the reaction of catalyzed carbonylation of the 3'--(2'-halo-biphenyl-4-ylmethyl)-1,7'-dimethyl-2'-propyl-1H,3'H- [2,5']bibenzoimidazolyl (TLMH) using either gaseous carbon monoxide in a solvent mixture containing water; or formic acid salts optionally together with acetic acid in anhydrous solvent.

Dans un mode de réalisation, l'invention porte sur la synthèse efficace d'une matière de départ biarylique halogénée par chimie de Grignard et sur l'utilisation de celle-ci. Dans un autre mode de réalisation, l'invention porte sur la réaction de carbonylation catalysée du 3'-(2'-halo-biphényl-4-ylméthyl)-1,7'-diméthyl-2'-propyl-1H,3'H-[2,5']bibenzoimidazolyle (TLMH) par monoxyde de carbone gazeux dans un mélange de solvants contenant de l'eau, ou par sels de l'acide formique facultativement conjointement à de l'acide acétique dans un solvant anhydre.

Affiliated with

Also associated with

Rating

Catalyzed carbonylation in the synthesis of angiotensin ii... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Catalyzed carbonylation in the synthesis of angiotensin ii..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Catalyzed carbonylation in the synthesis of angiotensin ii... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1602934