Catechol diethers as selective pde iv inhibitors

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 65/21 (2006.01) A61K 31/41 (2006.01) A61K 31/4427 (2006.01) A61K 31/4439 (2006.01) A61K 31/495 (2006.01) C07C 235/42 (2006.01) C07D 213/79 (2006.01) C07D 233/00 (2006.01) C07D 311/22 (2006.01) C07D 401/06 (2006.01) C07D 471/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2400368

This invention relates to 4-substituted catechol diether compounds which are selective inhibitors of phosphodiesterase (PDE) type IV. The compounds of the present invention are useful in inhibiting PDE IV and in the treatment of AIDS, asthma, arthritis, bronchitis, chronic obstructive airways disease, psoriasis, allergic rhinitis, dermatitis and other inflammatory diseases. This invention also relates to pharmaceutical compositions comprising the compounds hereof.

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