Catharanthus roseus binary alkaloid antimitotic derivatives

Details Catharanthus roseus binary alkaloid antimitotic derivatives Catharanthus roseus binary alkaloid antimitotic derivatives

C - Chemistry, Metallurgy

07

D

C07D 519/04 (2006.01) A61K 31/475 (2006.01)

Patent

CA 2167694

Novel fluorinated derivatives of the vinblastine and vinorelbine family of general formula (1) and the therapeutically acceptable salts of these molecules. The invention also concerns the application of said compounds in therapy and their methods of preparation.

Nouveaux dérivés fluorés de la famille de la vinblastine et de 1a vinorelbine correspondant à la formule générale (1) ainsi que les sels thérapeutiquement acceptables de ces molécules. L'invention concerne également (application de ces composés en thérapeutique et les procédés de préparation.

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