Cathepsin cysteine protease inhibitors

Details Cathepsin cysteine protease inhibitors Cathepsin cysteine protease inhibitors

C - Chemistry, Metallurgy

07

C

C07C 255/25 (2006.01) A61K 31/275 (2006.01) A61K 31/495 (2006.01) C07C 255/54 (2006.01) C07C 259/10 (2006.01) C07C 311/29 (2006.01) C07C 317/22 (2006.01) C07C 317/44 (2006.01) C07C 323/19 (2006.01) C07C 323/22 (2006.01) C07C 323/60 (2006.01) C07D 209/12 (2006.01) C07D 211/22 (2006.01) C07D 211/94 (2006.01) C07D 213/30 (2006.01) C07D 213/61 (2006.01) C07D 213/79 (2006.01) C07D 213/89 (2006.01) C07D 215/14 (2006.01) C07D 215/60 (2006.01) C07D 233/22 (2006.01) C07D 239/26 (2006.01) C07D 241/16 (2006.01) C07D 2

Patent

CA 2495939

This invention relates to class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis. They have the following structure: Formula (I).

La présente invention concerne une nouvelle classe de composés qui sont des inhibiteurs de protéases à cystéine, parmi lesquels entre autres, des inhibiteurs des cathepsines K, L, S et B. Ces composés sont utilisés pour traiter des maladies dans lesquelles l'inhibition de la résorption osseuse est recommandée, telles que l'ostéoporose. Ces composés sont représentés par la structure suivante: Formule (I).

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