Cathepsin cysteine protease inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 417/02 (2006.01) A61K 31/275 (2006.01) A61K 31/401 (2006.01) A61K 31/495 (2006.01) A61K 31/505 (2006.01) A61K 38/55 (2006.01) A61K 45/06 (2006.01) A61P 19/10 (2006.01) C07C 255/29 (2006.01) C07C 323/60 (2006.01) C07C 323/61 (2006.01) C07C 323/62 (2006.01) C07D 207/16 (2006.01) C07D 209/42 (2006.01) C07D 211/20 (2006.01) C07D 211/58 (2006.01) C07D 211/60 (2006.01) C07D 215/12 (2006.01) C07D 231/12 (2006.01) C07D 231/18 (2006.01) C07D 231/38 (2006.01) C07D 233/54 (2006.01) C07D 239/42 (2006.01) C07D 249/

Patent

CA 2439415

This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.

L'invention concerne une nouvelle classe de composés qui sont des inhibiteurs de la cystéine protéase comprenant de façon non limitative des inhibiteurs des cathépsines K, L, S et B. Ces composés sont utiles pour traiter des maladies à indication de résorption osseuse telles que l'ostéoporose.

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