C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/81 (2006.01) A61K 38/57 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2151059
A polypeptide having the amino acid sequence represented by the following SEQ ID NO: 1, and a cathepsin-L-specific inhibitor and an osteoporosis remedy each containing the polypeptide as the active ingredient. The polypeptide has such potent cathepsin-L-specific inhibitor and bone resorption inhibitor activities that it is useful for treating osteoporoses, in particular, senile osteoporosis.
Polypeptide doté de la séquence d'acides aminés ID NO:1, ainsi qu'inhibiteur spécifique de la cathepsine L et remède contre l'ostéoporose, contenant tous deux ledit polypeptide en tant qu'ingrédient actif. Ledit polypeptide possède des activités d'inhibition spécifique de la cathepsine L et de la résorption osseuse si fortes qu'il est utile pour traiter l'ostéoporose, en particulier l'ostéoporose sénile.
Katsunuma Nobuhiko
Turk Vito
Gowling Lafleur Henderson Llp
Taiho Pharmaceutical Co. Ltd.
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