Catheter injectable depot compositions and uses thereof

Details Catheter injectable depot compositions and uses thereof Catheter injectable depot compositions and uses thereof

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/34 (2006.01)

Patent

CA 2467239

Catheter injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having miscibility in water of less than or equal to 7 wt.% at 25~C, in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions are have substantially improved the shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection.

Cette invention concerne des compositions en dépôt injectables par cathéter renfermant un polymère bio-érodable et biocompatible, un solvant dans la miscibilité dans l'eau est inférieure ou égale à 7 % en poids à 25 ·C, en dose efficace pour plastifier le polymère et former un gel avec ledit polymère, un agent thixotropique, et un agent bénéfique. Le solvant comprend un alcool aromatique, un ester d'acide aromatique, un cétone aromatique, seuls ou mélangés les uns aux autres. Ces compositions se caractérisent par une capacité de fluidification sensiblement améliorée et par une force d'injection réduite, ce qui permet de les implanter facilement par injection sous la surface du corps du patient.

Affiliated with

Also associated with

Rating

Catheter injectable depot compositions and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Catheter injectable depot compositions and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Catheter injectable depot compositions and uses thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1985413