A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C12N 15/11 (2006.01) C12N 15/88 (2006.01)
Patent
CA 2210875
The present invention relates to an improved method for the cytoplasmic delivery of oligonucleotides using cationic copolymers based on vinyl alcohol with low levels of vinyl amine (PVAVAMs). Improved composition for use in such method are also provided.
Méthode améliorée pour l'introduction d'oligonucléotides dans le cytoplasme, grâce à des copolymères cationiques à base d'alcool vinylique à faible teneur en amine vinylique (PVAVAM). Composition améliorée adaptée à cette méthode.
Beekman Alice C.
Goldenberg Merrill S.
Amgen Inc.
Gowling Lafleur Henderson Llp
LandOfFree
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