C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A01H 5/00 (2006.01) A61K 38/17 (2006.01) C12N 15/12 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2491011
The invention concerns a peptide comprising or consisting of a first peptide sequence of formula (KLAKLAK), wherein K is lysine amino acid, L is leucine amino acid and A is alanine amino acid, and a second peptide sequence of formula (B), wherein B is a positively charged peptide of 4 to 15 amino acids with neutral pH, comprising or consisting of at least one peptide motif of formula .beta.XX.beta., wherein .beta. is a basic amino acid and X is any amino acid, and wherein, said first peptide sequence is repeated n times and said second peptide sequence is repeated m times, n and m being integers ranging between 1 and 5.
L'invention a pour objet un peptide comprenant ou consistant en une première séquence peptidique de formule (KLAKLAK), où K est l'acide aminé Lysine, L est l'acide aminé Leucine et A est l'acide aminé Alanine, et une seconde séquence peptidique de formule (B), où B est un peptide de 4 à 15 acides aminés chargé positivement à pH neutre, comprenant ou consistant en au moins un motif peptidique de formule BXXB, où B est un acide aminé basique et X est n'importe quel acide amine, et dans lequel, ladite première séquence peptidique est répétée n fois et ladite seconde séquence peptidique est répétée m fois, n et m étant des nombres entiers compris entre 1 et 5.
Cellectis
Diatos S.a.
Gowling Lafleur Henderson Llp
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