Cationic lipid formulation delivering nucleic acid to...

A - Human Necessities – 61 – K

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A61K 9/127 (2006.01) A61K 48/00 (2006.01) C12N 15/64 (2006.01) C12N 15/88 (2006.01)

Patent

CA 2326130

Methods of transfecting cells in vivo, including tumor cells in the peritoneal cavity are provided. Related lipid : nucleic acid formulations adapted to transfecting cells in the peritoneal cavity are provided. Assays, including high-throughput assays for screening lipid : nucleic acids are also provided.

Procédés de transfection de cellules in vivo, y compris des cellules tumorales de la cavité péritonéale. Formulations correspondantes de lipides et d'acides nucléiques conçues pour transfecter des cellules de la cavité péritonéale. Méthodes de dosage, y compris des méthodes à rendement élevé, servant à effectuer le criblage de lipides et d'acides nucléiques.

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