A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/107 (2006.01) A61K 9/00 (2006.01) A61K 31/5575 (2006.01) A61K 47/18 (2006.01) A61K 47/44 (2006.01) A61P 27/06 (2006.01)
Patent
CA 2754157
The present invention relates to a colloidal cationic oil-in-water emulsion comprising: -a prostaglandin, -an oil having a iodine value <= 2, -one or more surfactants including at least one quaternary ammonium compound, -water, wherein the prostaglandin/total sum of surfactants mass ratio is comprised between 0.5 and 5. The present invention also pertains to the use of said cationic oil-in- water emulsions for enhancing the stability of said prostaglandins, for the treatment of ocular hypertension and/or glaucoma, for promoting growth of eyelashes and/or for treating eyelash hypotrichosis.
La présente invention concerne une émulsion cationique colloïdale aqueuse réunissant une prostaglandine, une huile dont l'indice d'iode n'excède pas 2, au moins un tensioactif qui comporte au moins un composé ammonium quaternaire, et de l'eau, le rapport massique de la prostaglandine sur le total des tensioactifs restant compris entre 0,5 et 5. L'invention concerne également l'utilisation des ces émulsions cationiques aqueuses afin de renforcer la stabilité desdites prostaglandines, afin de traiter l'hypertension oculaire et/ou le glaucome, afin de favoriser la croissance des cils, et/ou afin de traiter l'hypotrichose des cils.
Garrigue Jean-Sebastien
Lallemand Frederic
Phillips Betty
Goudreau Gage Dubuc
Novagali Pharma Sa
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