Cationic polymers as toxin-binding agents

A - Human Necessities – 61 – K

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A61K 31/785 (2006.01) A61P 39/04 (2006.01)

Patent

CA 2303447

A method for treating pathogenic toxins in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising a cationic group attached to the polymer backbone. The polymer can be a homopolymer or a copolymer. In one embodiment, the polymer is a copolymer comprising a monomer having a pendant ammonium group and a hydrophobic monomer.

L'invention concerne un procédé permettant de traiter des toxines pathogènes chez un mammifère (par exemple, être humain), qui consiste à administrer audit mammifère une quantité thérapeutiquement efficace d'un polymère sur le squelette duquel est fixé un groupe cationique. Le polymère peut être un homopolymère ou un copolymère. Selon une variante, le polymère est un copolymère renfermant un monomère doté d'un groupe ammonium latéral et un monomère hydrophobe.

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