Cationic porphyrin derivatives and uses thereof

Details Cationic porphyrin derivatives and uses thereof Cationic porphyrin derivatives and uses thereof

C - Chemistry, Metallurgy

07

D

C07D 487/22 (2006.01) A61K 31/409 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2527155

A compound of formula (I): wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4 and Z have meanings given in the description, and metallated forms of such compounds, which are useful in the treatment of medical conditions for which a photodynamic compound is indicated. Pharmaceutical formulations and methods of treatment of a medical condition for which a photodynamic agent is indicated are also disclosed. Sterilising solutions comprising a compound of the invention, and the use thereof, are also disclosed.

L'invention concerne un composé de la formule I où X¿1?, X¿2?, X¿3?, X¿4?, Y¿1?, Y¿2?, Y¿3?, Y¿4? et Z ont les significations données dans la description, et les formes métallates de ces composés, qui sont utiles dans le traitement d'états médicaux pour lesquels un composé photodynamique est indiqué. L'invention concerne également les formulations pharmaceutiques et les procédés de traitement d'un état médical pour lequel un agent photodynamique est indiqué. L'invention concerne enfin la stérilisation de solutions contenant un composé de l'invention et son utilisation.

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