C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/88 (2006.01) A61K 9/127 (2006.01) A61K 31/7088 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2270396
The present invention relates to cationic cytofectins and liposomes comprising the same for use in delivering exogenous compounds into cells in vitro and in vivo. The liposome may comprise: (a) a neutral lipid such as dioleoylphosphatidylethanolamine (DOPE) or similar lipid-like compounds such as 1,2-dioleoyloxiphosphatidylethanolamine or other lipid-like structures and (b) one or more of the cationic cytofectins provided herein. The present invention also provides transfection kits and methods of delivery comprising the same.
L'invention concerne des cytofectines cationiques et des liposomes comprenant lesdites cytofectines, qui permettent d'introduire des composés exogènes dans des cellules in vitro et in vivo. Le liposome peut comprendre: (a) un lipide neutre tel que la dioléoylphosphatidyléthanolamine (DOPE) ou des composés de type lipidique similaires, tels que la 1,2-dioléoyloxyphosphatidyléthanolamine ou d'autres structures de type lipidique, et (b) une ou plusieurs cytofectines cationiques décrites ici. L'invention concerne également des trousses de transfection et des méthodes de délivrance les comprenant.
Erbacher Christoph
Weber Martin
Fetherstonhaugh & Co.
Qiagen Gmbh
LandOfFree
Cationic reagents for transfection does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cationic reagents for transfection, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cationic reagents for transfection will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1403466