Cationic steroid antimicrobial compositions and methods of use

Details Cationic steroid antimicrobial compositions and methods of use Cationic steroid antimicrobial compositions and methods of use

A - Human Necessities

61

K

A61K 31/56 (2006.01) A61K 31/568 (2006.01) A61K 31/57 (2006.01) A61K 31/575 (2006.01) A61K 45/06 (2006.01) A61P 31/18 (2006.01) G01N 33/15 (2006.01)

Patent

CA 2640584

The invention provides methods for decreasing or inhibiting human immunodeficiency virus (HIV) infection or pathogenesis (e.g., illness) of a cell in vitro, ex vivo or in vivo, a symptom or pathology associated with human immunodeficiency virus (HIV) infection or pathogenesis (e.g., illness) in vitro, ex vivo or in vivo, or an adverse side effect of human immunodeficiency virus (HTV) infection or pathogenesis (e.g , illness) in vitro, ex vivo or in vivo. In one embodiment, a method of the invention includes treating a subject with an invention compound (e.g., cationic steroid antimicrobial or CSA).

Cette invention concerne des méthodes visant à réduire ou à inhiber une infection par le virus de l'immunodéficience humaine (VIH) ou la pathogenèse (par exemple, maladie) d'une cellule in vitro, ex vivo ou in vivo, un symptôme ou une pathologie associé à l'infection par le virus de l'immunodéficience humaine (VIH) ou la pathogenèse (par exemple, maladie) in vitro, ex vivo ou in vivo, ou un effet secondaire indésirable de l'infection par le virus de l'immunodéficience humaine (VIH) ou la pathogenèse (par exemple, maladie) in vitro, ex vivo ou in vivo. Dans un mode de réalisation, une méthode de cette invention consiste à traiter un sujet avec un composé de cette invention (tel qu'un antimicrobien stéroïde cationique ou CSA).

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