Cationized antibodies against intracellular proteins

Details Cationized antibodies against intracellular proteins Cationized antibodies against intracellular proteins

A - Human Necessities

61

K

A61K 39/42 (2006.01) A61K 49/00 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2109093

2109093 9219971 PCTABS00017 The subject application discloses methods and compostions for the targeted detection and/or inhibition of an intracellular protein in a cell by contacting the cell with a cationized antibody which reacts specifically with the intracellular protein. An example of an intracellular protein which can be inhibited in this manner is the Tat protein which is encoded by the HIV-1 virus.

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