A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/136 (2006.01) A61K 31/03 (2006.01) A61K 31/167 (2006.01) A61K 31/17 (2006.01) A61K 31/222 (2006.01) A61K 31/352 (2006.01) A61K 31/40 (2006.01) A61K 31/403 (2006.01) A61K 31/43 (2006.01) A61K 31/437 (2006.01) A61K 31/44 (2006.01) A61K 31/473 (2006.01) A61K 31/655 (2006.01) A61P 3/10 (2006.01) A61P 11/06 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) A61P 31/04 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2336361
Method of identifying compounds that modulate intermolecular interactions between a target protein and a modifier are disclosed. Pharmaceutical composition comprising compounds that inhibit intermolecular interactions between a target protein and a modifier are disclosed. Methods of treating individual suffering from inflammatory conditions, undesirable immune responses, immunological conditions and bacterial infections are disclosed.
L'invention concerne une méthode permettant d'identifier des composés qui modulent des interactions intermoléculaires entre une protéine cible et un modificateur. L'invention concerne également des compositions pharmaceutiques comprenant des composés qui inhibent les interactions intermoléculaires entre une protéine cible et un modificateur. L'invention concerne également des méthodes de traitement d'un sujet souffrant de pathologies inflammatoires, de réactions immunitaires indésirables, de pathologies immunologiques ou d'infections bactériennes.
Greene Mark I.
Murali Ramachandran
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
The Trustees Of The University Of Pennsylvania
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