Cbh1 homologs and variant cbh1 cellulases

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/56 (2006.01) A23L 1/30 (2006.01) B27K 5/00 (2006.01) C11D 3/386 (2006.01) C12N 9/42 (2006.01) C12P 19/00 (2006.01)

Patent

CA 2519760

Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.

La présente invention a trait à un certain nombre d'homologues et variants de Hypocrea jecorina Cel7A (autrefois désignéTrichoderma reesei cellobiohydrolase I ou CBH1), à des acides nucléiques codant pour de tels homologues et leurs procédés de production. Les cellulases des homologues et variants comportent la séquence d'acides aminés d'une glycosyle hydrolase de la famille 7A dans laquelle un ou plusieurs acides aminés sont substitués et/ou délétés.

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